Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire information

What is Tadalafil?

Tadalafil is a brand name, generic Cialis, which is the samethat wasalso available as a branded.It is used to help treat erectile dysfunction (ED), also known as impotence, in men. It helps bystrongly shrink levels of blood vesselsidirectionally.

Tadalafil may be taken in two ways - either it contains

or as tablets.

Tadalafil tablets can be taken with or without food. However, a should not be taken daily as short-term treatment for ED or the use of ED medication alongside Tadalafil.

How much does Tadalafil cost?

At the time of writing, a starting price for Tadalafil 50mg was estimated at £ 13.74.

There are several generic Tadalafil brands available so- sighed, as the medical questionnaire included a list of all the medicines that you are prescribed from your GP. There were also a few brand names for Tadalafil such as Amlodipine, Flomax, Flonasex, Nardil, Pimozide and others.

Tadalafil is available in the following different doses for different indications:-

• Daily tablet:-

• Branded -

• Generic -

What is the difference between Tadalafil and Cialis?

Tadalafilis a prescription medication that is used to treat erectile dysfunction (ED) in men. It is awhich is taken either as needed or when needed, either before or shortly after sexual activity. It helps men to get and maintain an erection.

It is also available as a generic version of Cialis.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

EU federal authorities responsible for distributing medicines to the general public.

Medication	Legal Title	Drugs
Cialis	ikaan nisetuksen eline	Sildenafil
alpha-blocker	Pantoprazole	Tadalafil

F.

Here are the drug-food interactions to be aware of:

1. : Though not a direct interaction, combining Cialis with high alcohol consumption might worsen side effects like headaches or increase heart rate in sensitive individuals.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

EU Anticisspo Oncology and Caspofoxie (tumescIts)

Cialis (tadalafil) is an inhibitor of the enzyme PDE5, which is responsible for breaking down a molecule called cyclic guanosine monophosphate (cGMP). By inhibiting PDE5, Cialis breaks cGMP, leading to increased blood flow to the penis, causing discomfort and nausea. This may result in dizziness or fainting, with symptoms such as nausea, vomiting, lightheadedness, and muscle cramps. If these effects occur, consult your doctor for advice.

C.

Tadalafil (and other drugs used to treat erectile dysfunction) can interact with certain foods and beverages, such as those that contain fat. It is important to distinguish between pharmacological and direct interactions.

1. Caffeinated beverages may decrease the effectiveness of tadalafil and may enhance its bioavailability. However, it is not recommended to take Cialis together with these products.

SUMMARY CMI

Cialis

Consumer Medicine Information (CMI) summary

The on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist.

1. Why am I using Cialis 12.34?

Cialis contains tadalafil. Tadalafil is used to treat erectile dysfunction (ED) and enlarged prostate. It is also used to treat symptoms of benign prostatic hyperplasia (BPH). Cialis works by relaxing the muscles in the blood vessels in the penis, allowing increased blood flow into the penis and causing an erection. This helps you achieve and maintain an erection. Tadalafil is available in the form of tablets.

For more information, see in the full CMI.

2. What should I know before I use Cialis?

Do not use if you have ever had an allergic reaction to tadalafil or any of the ingredients listed at the end of the CMI.

Talk to your doctor if you have any other medical conditions, take any other medicines, or are pregnant or plan to become pregnant or are breastfeeding.

4. How do I use Cialis?

• Take Cialis exactly as it was prescribed for you.
• Swallow the tablet whole with a glass of water.
• Do not crush, chew or break the tablet.

More instructions can be found in in the full CMI.

5. What should I know while using Cialis?

Things you should do	Remind any doctor, dentist or pharmacist you visit that you are using Cialis. If you are 65 years or older, tell your doctor that you are taking Cialis. If you are under 18 years of age, tell your doctor that you are taking Cialis. If you are under 20 years of age, tell your doctor that you are taking Cialis. If you are 20 years or older, tell your doctor that you are taking Cialis.
Things you should not do	Do not give Cialis to anyone else, even if they have the same condition as you.
Driving or using machines	Cialis may cause dizziness or fainting, so don’t drive or operate machinery until you know how it affects you.
Looking after your medicine	Store below 25°C.

6. Are there any side effects?

Stop taking Cialis if you notice any of the following:

• Sudden vision loss
• Nasal congestion
• Sudden priapism (prolonged erection)
• Fainting
• Chest pain
• Sudden dizziness
• Sudden numbness or weakness
• Sudden vision loss in one or both eyes

For more information, including what to do if you have any side effects, see in the full CMI.

Tadalafil is a phosphodiesterase (PDE-5) inhibitor. It relaxes the muscles in the blood vessels in the penis, allowing increased blood flow into the penis and causing an erection. Tadalafil relaxes the muscles in the prostate and bladder. It works by increasing urine flow and relaxing the muscles in these organs.

Cialis is used to treat erectile dysfunction (ED), enlarged prostate, and benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the bladder and prostate.